I thought this one might be. Well, in this case, it should be enough to go in Safepay Settings tab, and for the domain you have trouble with (web.mail.comcast.net) select the option "Do not use secure browser":
For the options Yes/No and Remember checkbox, I was thinking that you clicked on the alert that appeared when Bitdefender prompts you to open (or not) a website in Safepay.
As for "Do not use Safepay" option, it does not render Safepay useless - you can still open it manually and navigate to the website of choice (either typing directly the URL as in any other browser, or having websites saved in Favorites and clicking from there). It just means that the automatic behavior won't be used - simply speaking, when Bitdefender detects that, say, you open a banking URL in Internet Explorer, it offers to open the same URL in Safepay (that is done by detecting in our cloud database if a website is bank or not).
For any other details, do not hesitate to contact us in forum !
Regards,
Cristian