How to remove Critical threats? MacOS Big Sur 11.6 (20G165)

Maxpax

Under Notifications in the critical tab I have many entries "Threat requires removal"
Feature: Antivirus
We identified a threat that needs to be manually removed.
Threat name: URL.Spam.Heur.4
Path: /Volumes/My Book Thunderbolt Duo/Email Archiver Pro/email address/INBOX.Archive/2017/08/2017-08-28 10.11.16Z What Will You Buy with Your $50-Amazon Award #5295328.pdf=>(URI)

How do I delete this file? Must be an easy way rather than looking up each one manually.

DebbyR

I have Mac OS 11.6
I get the message Critical Manual delete. The culprit is Adware.MAC.Pirrit.KW
Path: /Volumes/com.apple.TimeMachine.localsnapshots/Backups.backupdb/Dennis’s iMac/2021-10-03-195118/Macintosh HD - Data/.Spotlight-V100/Store-V2/B01F995F-18EE-48B6-9933-3DD04F055D40/Cache/0000/0003/009e/12895308098.txt

Aby ideas on how to remove this. It all started after I ran Time Machine. many thanks.