Is Windows Core Isolation compatible with Bitdefender total security?
I did a google research and i could find only one answer to your question here:
Like stated in the answer: "You will have to try it to see how they play together.".
You should also contact Bitdefender Consumer Support by chat, telephone or e-mail:
NOTE: Bitdefender telephone support is not toll-free!
Maybe @Alexandru_BD and @Mike_BD can give you more informations.
@Gjoksi summed it up well in his post above, you'll have to give it a go to see how they get along together.