Bitdefender Requesting Access to 40+ Connections

Using Little Snitch coupled with Bitdefender for Mac.  Running El Capitan 10.11.4 on iMac with Retina, using Firefox 55.0.3 (64-bit).  Bitdefender asks to connect to the following servers ROUTINELY (i.e., every day), via the listed ports and protocols.  Are these all legit?  If they are, isn't this extremely inefficient?  To say the least, it's annoying.

A.  bdagentd:

(1) 54.210.126.134 (TCP 443);

(2) 216.xx.******.3 (UDP 53); 

(3) 216.xx.******.2 (UDP 53);

(4) 81.161.59.90 (TCP 80);

(5) nimbus.bitdefender.net (TCP 443);

(6) elb-nvi-amz.nimbus.bitdefender.net (TCP 443);

(7) elb-tky-amz.nimbus.bitdefender.net (TCP 443);

(8) elb-fra-amz.nimbus.bitdefender.net (TCP 443);

(9) elb-iri-amz.nimbus.bitdefender,net (TCP 443);

(10) 35.167.28.164 in domain nimbus.bitdefender.net (TCP 443);

(11) 54.213.119.76 in domain nimbus.bitdefender.net (TCP 443)

B.  BDCoreIssues:

(12) 52.45.110.161 (TCP 443);

(13) 216.xx.******.2 (UDP 53);

(14) 81.161.59.89 (TCP 80);

(15) nimbus.bitdefender.net (TCP 443);

(16) elb-fra-amz.nimbus.bitdefender.net (TCP 443);

(17) 216.xx.******.3 (UDP 53);

(18) elb-irl-amz.nibus.bitdefender.net (TCP 443);

(19) 52.40.128.18 in domain nimbus.bitdefender.net (TCP 443);

(20) elb-nvi-amz.nimbus.bitdefender.net (TCP 443);

(21) elb-tky-amz.nimbus.bitdefender.net (TCP 443);

(22) 54.70.243.192 9n domain nimbus.bitdefender..... (TCP 443);

(23) elb-nvi-amz.nimbus.bitdefender.net (TCP 80)

C.  BDLDaemon:

(24) 52.4.148.25 (TCP 443);

(25) 216.xx.******.2 (UDP 53);

(26) 216.xx.******.3 (UDP 53);

(27) 52.27.175.34 in domain nimbus.bitdefender.net (TCP 443);

(28) 54.69.9.185 in domain nimbus.bitdefender.net (TCP 443);

(29) elb-ore-amz.nimbus.bitdefender.net (TCP 443);

(30) elb-nvi-amz.nimbus.bitdefender.net (TCP 443);

(31) elb-tky-amz.nimbus.bitdefender.net (TCP 443);

(32) elb-irl-amz.nimbus.bitdefender.net (TCP 443);

(33) elb-fra-amz.nimbus.bitdefender.net (TCP 443);

D.  BDUpdDaemon:

(34) upgrade.bitdefender.com (TCP 80);

(35) nimbus.bitdefender.net (TCP 443);

(36) 216.xx.******.2 (UDP 53);

(37) 216.xx.******.3 (UDP 53);

(38) elb-iri-amz.nimbus.bitdefender.net (TCP 443);

(39) elb-nvi-amz.nimbus.bitdefender.net (TCP 443);

(40) elb.tky.amz.nimbus.bitdefender.net (TCP 443);

(41) elb-fra-amz.nimbus.bitdefender.net (TCP 443);

(42) elb-irl-amz.nimbus.bitdefender.net (TCP 443);

(43) 52.25.136.108 in domain nimbus.bitdefender.net (TCP 443);

E.  Antivirus for Mac:

(44) ipm.bitdefender.com (TCP 443).

Thanks for your assistance in this annoying and perplexing matter!