Safe Mode: How To Scan More Than Just Files?

Hi. I know that I can run a scan in Safe Mode using Manual Scan. But it only lets me select files and folders. Even though this can include all files and folders on my system, I want it to do the deeper scanning that includes boot, memory, registry, etc. In fact, scanning these components would seem especially important in a situation where one has the need to use Safe Mode. How can I accomplish this? I saw a command-line approach in a 2007 post, but the path given no longer applies, and I can't find a suitable replacement Thanks.