Well, I'm not really sure if it is a real issue or not but here's the info:
Monday morning (Eastern Standard Time): Virus Signatures: 6571473, Engine Version: 7.33004
The next update, after I returned from work, update which included the fix for the Firefox Antiphishing toolbar ...
Monday afternoon (Eastern Standard Time): Virus Signatures: 6188380, Engine Version: 7.33012
Now it's Thursday afternoon (Eastern Standard Time) and the numbers say: Virus Signatures: 6193803, Engine Version: 7.33076
All updates performed normally from Monday till today, there were no issues whatsoever. What drew my attention to this was a post on the French forum where someone else has the same problem.
What happened with the number of signatures on Monday? Why did it drop by 40,000 so suddenly?