Evil McAfee puppy is haunting me

I have a popup haunting me. It's not regulated just to a browser, it is stuck to the screen like a demon! Bit Defender is not catching it, and I can't figure out how to get rid of it. I uninstalled the Opera browser in case that was where it came in. I didn't care that much for the browser anyway. For right now I am stuck either waiting 5-20 min for the puppy to wander off on it's own or clicking the damn link, trying to close it, telling it sure I'll take the discount, and then being able to close that page. And it doesn't open up in a browser, it opens up in it's own little box like the demon child it is so I can't even tell what scam site it's going to. Please tell me how to send the puppy away!!!

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