In certain occasions...
e.g. after a disinfection (incl. generic false positives), Bitdefender will block certain Windows Features for security, such as and especially Hidden
and ShowSuperHidden
in HKCU\Software\Microsoft\Windows\CurrentVersion\Explorer\Advanced
.
If the machine is not rebooted but e.g. Hibernate is used and a user does not suspect the Anti-Virus to cause this behavior, it can be a little misleading trying to enable hidden files/folders in the explorer settings or - because it does not work - finally in the registry, seeing that it won't work and not knowing the cause. This applies especially to Free-/Home-users.
If it was possible to detect the user trying to change these settings, a popup message could be nice indicating, that it is blocked on purpose. If it isn't by implementation just forget about this. Otherwise: Especially when working with open-source-stuff and having false-positive indications - maybe to your own software - you may not reboot your computer immediately after a detection.
And if you do not know this behavior of Bitdefender and you suspect your system to be broken, especially medium-experienced users may start messing up their system before thinking of the classic cliché of "Just reboot your machine".